Professor Balandin’s invited talk at the Materials Research Society (MRS) meeting was selected for the live keynote presentation in the session “2D Atomic and Molecular Sheets—Electronic and Photonic Properties and Device Applications.” Professor Balandin delivered a talk entitled “Electronic Properties and Device Applications of Quasi 2D Charge Density Wave Materials.” The charge density wave (CDW) phase is a quantum state consisting of a periodic modulation of the electronic charge density accompanied by a periodic distortion of the atomic lattice in quasi-1D or quasi-2D metallic crystals. Several layered transition metal dichalcogenides (TMDs) exhibit unusually high transition temperatures to different CDW symmetry-reducing phases opening possibility for practical device applications. The talk presents the room-temperature voltage-controlled oscillators and logic circuits, which operate on the basis of the CDW transitions in 2D materials, triggered by the applied voltage. It is found that the 2D CDW devices reveal exceptional hardness against X-ray and proton radiations. The live keynote MRS presentation slides are available at the link.